Condensed Consolidated Statements of Operations (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2014	Jun. 30, 2013	Jun. 30, 2014	Jun. 30, 2013
Revenues:
Product sales, net	$ 21,955	$ 4,801	$ 39,826	$ 5,455
Royalties	34,172	31,704	60,341	56,484
Total revenues	56,127	36,505	100,167	61,939
Cost of sales	2,737	473	4,614	538
Operating expenses:
Research and development	21,151	30,888	41,708	46,583
Selling, general and administrative	26,449	14,465	51,003	28,670
Total operating expenses	47,600	45,353	92,711	75,253
Operating income (loss)	5,790	(9,321)	2,842	(13,852)
Other income (expense)
Interest income, net	103	58	224	113
Interest expense	(3,648)	(3,034)	(7,683)	(6,429)
Other	10	(88)	307	(13)
Total other expense, net	(3,535)	(3,064)	(7,152)	(6,329)
Income (loss) before income tax expense	2,255	(12,385)	(4,310)	(20,181)
Income tax expense	263	4	274	4
Net income (loss)	$ 1,992	$ (12,389)	$ (4,584)	$ (20,185)
Net income (loss) per common and potential common share
Basic	$ 0.02	$ (0.13)	$ (0.04)	$ (0.22)
Diluted	$ 0.02	$ (0.13)	$ (0.04)	$ (0.22)
Weighted average common and potential common shares outstanding
Basic	106,807	97,321	105,218	92,886
Diluted	110,503	97,321	105,218	92,886