Condensed Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified	9 Months Ended
	Sep. 30, 2012	Sep. 30, 2011
Cash flows from operating activities:
Net loss	$ (6,532)	$ (27,631)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	799	293
Accretion of premium (discount) on marketable investment securities	1,550	1,024
Non-cash interest expense	13,727	11,768
Non-cash royalties	(45,878)	(30,653)
Loss on extinguishment of debt	0	646
Compensation expense on share-based awards	4,879	3,006
Realized gain on sale of marketable investment securities	(3)	0
(Increase) decrease in operating assets:
Accounts receivable	(14,865)	17,717
Prepaid expenses, other current assets and other assets	3,182	(3,147)
(Decrease) increase in operating liabilities:
Accounts payable and accrued expenses	2,176	(2,480)
Other liabilities	(1,168)	(463)
Net cash used in operating activities	(42,133)	(29,920)
Cash flows from investing activities:
Sales of marketable investment securities	2,526	240
Maturities of marketable investment securities	76,914	63,568
Purchases of marketable investment securities	(67,668)	(47,645)
Acquisitions of property and equipment	(858)	(1,964)
Net cash (used in) provided by investing activities	10,914	14,199
Cash flows from financing activities:
Principal payments on debt	0	(215,033)
Proceeds from issuance of non-recourse debt	0	145,000
Payment of debt issuance costs		(96)
Net proceeds from the sale of common stock and exercise of stock options	903	108,118
Decrease in restricted cash and cash equivalents	0	50,784
Net cash provided by financing activities	903	88,773
Effect of exchange rate changes on cash	(13)	8
Net (decrease) increase in cash and cash equivalents	(30,329)	73,060
Cash and cash equivalents at beginning of period	82,401	77,170
Cash and cash equivalents at end of period	52,072	150,230
Supplemental Disclosures of Cash Flow Information
Cash paid for interest	714	26,869
Cash paid for income taxes	0	0
Supplemental Disclosure of Non-cash Investing and Financing Activities
Unrealized gains on marketable investment securities	138	(45)
Accrued acquisition of property and equipment	45	231
Noncash reduction of debt	44,971	0
Conversion of 5.75% convertible notes	$ 0	$ 33,260