Condensed Consolidated Statements of Operations (USD $) In Thousands, except Share data, unless otherwise specified	3 Months Ended		6 Months Ended
	Jun. 30, 2012	Jun. 30, 2011	Jun. 30, 2012	Jun. 30, 2011
Revenues
Royalties	$ 28,517	$ 27,210	$ 51,441	$ 45,761
Sale of royalty rights	25,000	0	25,000	0
Milestones and license fees	0	0	0	5,025
Total revenues	53,517	27,210	76,441	50,786
Operating expenses
Cost of royalties	0	500	0	500
Cost of license fees	0	0	0	2,538
Research and development	32,641	17,135	52,840	32,040
General and administrative	9,670	5,539	17,440	10,615
Total operating expenses	42,311	23,174	70,280	45,693
Operating income	11,206	4,036	6,161	5,093
Other income (expense)
Interest income, net	76	109	160	190
Interest expense	(4,467)	(10,330)	(10,001)	(20,561)
Other	540	53	472	14
Total other expense, net	(3,851)	(10,168)	(9,369)	(20,357)
Income (loss) before income tax expense	7,355	(6,132)	(3,208)	(15,264)
Income tax expense	0	0	0	18
Net income (loss)	$ 7,355	$ (6,132)	$ (3,208)	$ (15,282)
Net income (loss) per common and potential common share
Basic	$ 0.08	$ (0.07)	$ (0.04)	$ (0.20)
Diluted	$ 0.08	$ (0.07)	$ (0.04)	$ (0.20)
Weighted average common and potential common shares outstanding
Basic shares	86,903,000	83,200,000	86,880,000	75,691,000
Diluted shares	91,470,000	83,200,000	86,880,000	75,691,000