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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Cash flows from operating activities:      
Net loss $ (10,668,000) $ (32,048,000) $ (31,483,000)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 747,000 998,000 607,000
Stock-based compensation 719,000 2,155,000 3,650,000
Amortization of intangible assets 112,000 111,000 321,000
Impairment of goodwill   9,858,000  
Amortization of debt issuance costs 45,000 37,000  
Accrued interest 898,000 650,000  
(Gain) loss on disposal of assets (12,000) 4,000  
Changes in assets and liabilities:      
Accounts receivable (1,122,000) 170,000 (552,000)
Inventories (315,000) 146,000 (716,000)
Prepaid expenses and other assets (1,016,000) 459,000 104,000
Accounts payable (402,000) (419,000) 261,000
Deferred revenue and other liabilities 3,435,000 (64,000) 334,000
Net cash used in operating activities (7,579,000) (17,943,000) (27,474,000)
Cash flows from investing activities:      
Purchases of property and equipment (300,000) (646,000) (1,202,000)
Net proceeds from sale of assets 12,000    
Proceeds from sales and maturities of marketable securities 2,604,000 50,486,000 44,953,000
Purchases of marketable securities (1,602,000) (36,874,000) (36,873,000)
Net cash provided by investing activities 714,000 12,966,000 6,878,000
Cash flows from financing activities:      
Proceeds from sale of common stock, net of issuance costs 1,967,000 364,000 23,140,000
Proceeds from the issuance of notes payable, net of issuance costs   7,877,000  
Payments on capital lease obligations   (138,000) (14,000)
Net cash provided by financing activities 1,967,000 8,103,000 23,126,000
Net increase (decrease) in cash and cash equivalents (4,898,000) 3,126,000 2,530,000
Cash and cash equivalents at beginning of period 8,766,000 5,640,000  
Cash and cash equivalents at end of period 3,868,000 8,766,000 5,640,000
Supplemental disclosure:      
Issuance of convertible notes in settlement of accrued interest 854,000 336,000  
Cash paid for income taxes $ 2,000 $ 21,000 $ 56,000