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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Cash flows from operating activities:    
Net loss $ (10,142,000) $ (17,570,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 573,000 780,000
Stock-based compensation 552,000 1,794,000
Amortization of intangible assets 84,000 83,000
Amortization of debt issuance costs 33,000 23,000
Accrued interest 656,000 440,000
(Gain)/loss on disposal of assets (12,000) 5,000
Changes in assets and liabilities:    
Accounts receivable (1,160,000) 103,000
Inventories 205,000 173,000
Prepaid expenses and other assets (1,289,000) 343,000
Accounts payable (390,000) (759,000)
Deferred revenue and other liabilities 1,931,000 (383,000)
Net cash used in operating activities (8,959,000) (14,968,000)
Cash flows from investing activities:    
Purchases of property and equipment (26,000) (646,000)
Proceeds from sales and maturities of marketable securities 2,604,000 40,612,000
Purchases of marketable securities (1,602,000) (28,749,000)
Net cash provided by investing activities 988,000 11,217,000
Net proceeds from sale of assets 12,000  
Cash flows from financing activities:    
Net proceeds from issuance of common stock 1,989,000 363,000
Proceeds from the issuance of notes payable, net of issuance costs   7,879,000
Payments on capital lease obligations   (123,000)
Net cash provided by (used in) financing activities 1,989,000 8,119,000
Net increase (decrease) in cash and cash equivalents (5,982,000) 4,368,000
Cash and cash equivalents at beginning of period 8,766,000 5,640,000
Cash and cash equivalents at end of period 2,784,000 10,008,000
Supplemental disclosure:    
Issuance of convertible notes in settlement of accrued interest $ 854,000 $ 336,000