CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016
Net revenue
Product	$ 955	$ 1,120
Royalty and other	257	331
Total net revenue	1,212	1,451
Cost of net revenue	602	863
Gross profit	610	588
Operating expenses
Research and development	3,485	5,232
Selling, general and administrative	1,314	1,516
Restructuring charges		676
Total operating expenses	4,799	7,424
Loss from operations	(4,189)	(6,836)
Interest expense	224	33
Other income, net	13	24
Loss before income taxes	(4,400)	(6,845)
Income tax provision	5	20
Net loss	(4,405)	(6,865)
Other comprehensive income (loss), net of tax:
Net unrealized gains (losses) on available-for-sale securities		16
Comprehensive loss	$ (4,405)	$ (6,849)
Net loss per share
Basic and diluted	$ (0.66)	$ (1.05)
Shares used in computing net loss per share
Basic and diluted	6,647	6,567