CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Net revenue
Product	$ 1,287	$ 543	$ 2,407	$ 723
Royalty and other	346	451	677	1,047
Total net revenue	1,633	994	3,084	1,770
Cost of net revenue	963	563	1,826	800
Gross profit	670	431	1,258	970
Operating expenses
Research and development	4,884	5,789	10,116	12,682
Selling, general and administrative	1,577	1,550	3,093	3,164
Restructuring charges			676
Total operating expenses	6,461	7,339	13,885	15,846
Loss from operations	(5,791)	(6,908)	(12,627)	(14,876)
Interest expense	(213)		(247)
Other income, net	20	29	45	52
Loss before income taxes	(5,984)	(6,879)	(12,829)	(14,824)
Income tax provision	20	27	40	47
Net loss	(6,004)	(6,906)	(12,869)	(14,871)
Other comprehensive income (loss), net of tax:
Net unrealized gains (losses) on available-for-sale securities		(5)	16	1
Comprehensive loss	$ (6,004)	$ (6,911)	$ (12,853)	$ (14,870)
Net loss per share
Basic and diluted (in dollars per share)	$ (0.09)	$ (0.11)	$ (0.20)	$ (0.25)
Shares used in computing net loss per share
Basic and diluted (in shares)	65,985	64,737	65,830	59,539