X0202 4 2004-08-13 1 0000889057 TULARIK INC TLRK 0001182474 SAXTON CRAIG APD C/O TULARIK INC. 1120 VETERANS BLVD. SO. SAN FRANCISCO CA 94080 1 0 0 0 Common Stock 2004-08-13 4 D 0 25000 D 0 D Stock Option (right to buy) 22.62 2004-08-13 4 D 0 25000 D 2011-09-08 Common Stock 25000 0 D Stock Option (right to buy) 14.40 2004-08-13 4 D 0 10000 D 2012-04-17 Common Stock 10000 0 D Stock Option (right to buy) 5.17 2004-08-13 4 D 0 10000 D 2013-04-22 Common Stock 10000 0 D Disposed of pursuant to merger agreement between issuer and Amgen Inc. in exchange for 11,275 shares of Amgen common stock having a market value of $55.432 per share pursuant to the terms of the merger agreement. This option, which provided for vesting in equal annual installments over a four-year period until full vest on September 9, 2005, was assumed by Amgen, Inc. in the merger and replaced with an option to purchase 11,275 shares of Amgen common stock for $50.16 per share. This option, which provided for vesting in equal annual installments over a four-year period until full vest on April 18, 2006, was assumed by Amgen, Inc. in the merger and replaced with an option to purchase 4,510 shares of Amgen common stock for $31.93 per share. This option, which provided for vesting in equal annual installments over a four-year period until full vest on April 23, 2007, was assumed by Amgen, Inc. in the merger and replaced with an option to purchase 4,510 shares of Amgen common stock for $11.47 per share. Valerie L. Pierce, as Attorney in Fact for Craig A.P.D. Saxton 2004-08-16