Organization (Details) $ in Thousands	3 Months Ended
	Mar. 31, 2022 USD ($) product segment	Mar. 31, 2021 USD ($)	Dec. 31, 2021 USD ($)
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Number of therapy products | product	2
Number of reportable segments | segment	1
Accumulated deficit	$ 390,377		$ 383,286
Net loss	7,091	$ 3,289
Cash and cash equivalents	55,659	$ 58,154	$ 68,330
Short term investments	$ 67,700