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Stock-based Compensation - Non-cash Stock-based Compensation Expense (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Non-cash stock-based compensation expense $ 1,932 $ 755 $ 5,739 $ 2,053
Cost of goods sold        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Non-cash stock-based compensation expense 284 119 820 316
Research and development        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Non-cash stock-based compensation expense 365 177 1,282 391
Selling, general and administrative        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Non-cash stock-based compensation expense $ 1,283 $ 459 $ 3,637 $ 1,346