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Revenue (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
Disaggregation of Revenue [Line Items]          
Product sales, net $ 22,484 $ 14,260 $ 59,522 $ 40,574  
Accounting Standards Update 2014-09 | Difference between Revenue Guidance in Effect before and after Topic 606          
Disaggregation of Revenue [Line Items]          
Product sales, net 125 372 (273) 230  
Implants | Contracted rate | Third party distributor          
Disaggregation of Revenue [Line Items]          
Product sales, net 243 8,046 18,354 11,145  
Implants | Third party reimbursement | Third party distributor          
Disaggregation of Revenue [Line Items]          
Product sales, net 15,593 1,079 23,156 15,172  
Biopsy kits | Direct bill          
Disaggregation of Revenue [Line Items]          
Product sales, net 488 412 1,392 1,274  
Epicel | Direct bill          
Disaggregation of Revenue [Line Items]          
Product sales, net 6,035 $ 4,351 16,893 $ 12,753  
License Grants, Milestone and Royalty Payments | Innovative Cellular Therapeutics          
Disaggregation of Revenue [Line Items]          
Product sales, net         $ 1,200
Agreement with Orsini, Potential Payment if Minimum Payment Obligations Not Achieved          
Disaggregation of Revenue [Line Items]          
Incremental service fee $ 1,300   $ 1,300