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Revenue (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Dec. 31, 2017
Disaggregation of Revenue [Line Items]      
Revenue $ 18,027 $ 9,361  
Accounting Standards Update 2014-09 | Difference between Revenue Guidance in Effect before and after Topic 606      
Disaggregation of Revenue [Line Items]      
Revenue (138) (2,114)  
Implants | Contracted rate | Third party distributor      
Disaggregation of Revenue [Line Items]      
Revenue 10,749 297  
Implants | Estimated payments | Third party distributor      
Disaggregation of Revenue [Line Items]      
Revenue 1,008 6,385  
Biopsy kits | Direct bill      
Disaggregation of Revenue [Line Items]      
Revenue 436 439  
Epicel | Direct bill      
Disaggregation of Revenue [Line Items]      
Revenue $ 5,972 $ 4,354  
License Grants, Milestone And Royalty Payments | Innovative Cellular Therapeutics      
Disaggregation of Revenue [Line Items]      
Revenue     $ 1,200