CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Income Statement [Abstract]
Product sales, net	$ 54,383	$ 51,168	$ 28,796
Cost of product sales	28,307	26,470	17,293
Gross profit	26,076	24,698	11,503
Research and development	15,295	18,890	21,263
Selling, general and administrative	27,388	22,479	13,774
Loss on impairment of intangible asset	2,638	0	0
Total operating expenses	45,321	41,369	35,037
Loss from operations	(19,245)	(16,671)	(23,534)
Other income (expense):
(Increase) decrease in fair value of warrants	0	324	(27)
Bargain purchase gain	0	0	3,473
Foreign currency translation gain (loss)	(5)	(67)	152
Interest income	8	36	24
Other income (expense)	(10)	47	(2)
Interest expense	(314)	(9)	(6)
Total other income (expense)	(321)	331	3,614
Net loss	$ (19,566)	$ (16,340)	$ (19,920)
Net loss per share attributable to common shareholders (basic and diluted) (in dollars per share)	$ (1.18)	$ (0.97)	$ (2.23)
Weighted average number of common shares outstanding (Basic and Diluted) (in shares)	23,093	23,760	11,642