Acquisitions (Details) $ in Thousands		3 Months Ended		12 Months Ended
	May. 30, 2014 USD ($) patent	Jun. 30, 2014 USD ($)	Mar. 31, 2013 USD ($)	Dec. 31, 2015 USD ($)	Dec. 31, 2014 USD ($)	Dec. 31, 2013 USD ($)
Total purchase price allocation
Asset retirement obligation				$ 0	$ (348)
Bargain purchase gain				$ 0	(3,473)	$ 0
Restructuring charge			$ 400
CTRM Business
Business Acquisition [Line Items]
Number of patents and patents applications acquired (over) | patent	250
Total purchase price consideration
Cash payment	$ 4,000
Promissory note	2,500
Total acquisition consideration	6,500
Total purchase price allocation
Cash	5,050
Accounts receivable	53
Inventory	2,039
Other current assets	192
Accounts payable and accrued expenses	(939)
Asset retirement obligation	(1,600)
Property and equipment	1,818
Intangible assets	3,360
Bargain purchase gain	(3,473)	$ (3,500)
Total consideration	$ 6,500
Restructuring charge					3,000
Unaudited pro forma condensed combined statements
Pro forma revenue					44,906	43,863
Pro forma net loss					$ (30,115)	$ (49,124)
CTRM Business | Commercial rights
Identifiable intangible assets acquired and their estimated useful lives
Useful Life	12 years
CTRM Business | Sanofi | Denmark
Total purchase price allocation
Cash received in order to fund the restructuring of the Denmark operations and close the facility	$ 5,000