<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2013-08-16</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000887359</issuerCik>
        <issuerName>AASTROM BIOSCIENCES INC</issuerName>
        <issuerTradingSymbol>ASTM</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001408408</rptOwnerCik>
            <rptOwnerName>Eastern Capital LTD</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>P. O. BOX 31363</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>GRAND CAYMAN</rptOwnerCity>
            <rptOwnerState>E9</rptOwnerState>
            <rptOwnerZipCode>KY1-1206</rptOwnerZipCode>
            <rptOwnerStateDescription>CAYMAN ISLANDS</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001488856</rptOwnerCik>
            <rptOwnerName>Portfolio Services Ltd.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>45 MARKET STREET, SUITE 3211, CAMANA BAY</rptOwnerStreet1>
            <rptOwnerStreet2>P.O. BOX 31363</rptOwnerStreet2>
            <rptOwnerCity>GRAND CAYMAN</rptOwnerCity>
            <rptOwnerState>E9</rptOwnerState>
            <rptOwnerZipCode>KY1-1206</rptOwnerZipCode>
            <rptOwnerStateDescription>CAYMAN ISLANDS</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001331271</rptOwnerCik>
            <rptOwnerName>DART KENNETH BRYAN</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>P. O. BOX 31300</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>GRAND CAYMAN</rptOwnerCity>
            <rptOwnerState>E9</rptOwnerState>
            <rptOwnerZipCode>KY1-1206</rptOwnerZipCode>
            <rptOwnerStateDescription>CAYMAN ISLANDS</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>8499769</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Warrants</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.375</value>
                <footnoteId id="F2"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2013-08-16</value>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F1"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>7250000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Series B-2 Voting Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>3.25</value>
                <footnoteId id="F3"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <value>2017-03-09</value>
                <footnoteId id="F3"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F3"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>12308000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Series B-1 Non-Voting Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F4"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F4"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F4"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Series B-2 Voting Preferred Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>2213559</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The warrants are immediately exercisable and expire on the fifth anniversary of the date of issuance.</footnote>
        <footnote id="F2">The reported securities are included within 7,250,000 Units purchased by Eastern Capital Limited.  Each Unit consists of one share of common stock and one warrant to purchase one share of common stock at an exercise price of $0.375 per share.</footnote>
        <footnote id="F3">Each share of Series B-2 Voting Preferred Stock is convertible, at the option of Eastern Capital Limited at any time after March 9, 2017 into a number of shares of the Company common stock equal to the original issue price per share of Series B-2 Voting Preferred Stock of $3,250 divided by the conversion price of $3.25, except as otherwise provided in the Amended and Restated Certificate of Designations, Preferences and Rights. In addition, under certain circumstances, at any time after March 9, 2017, the Issuer may elect to convert all or a portion of the Series B-2 Voting Preferred Stock into shares of common stock at the same rate. The Series B-2 Voting Preferred Stock has no expiration date.</footnote>
        <footnote id="F4">Until March 9, 2017, the shares of Series B-2 Voting Preferred Stock held by Eastern Capital Limited accrue dividends at a rate  of 11.5%  per annum of the original issue price, payable through the issuance of shares of Series B-1 Non-Voting Preferred Stock. Each share of Series B-1 Non-Voting Preferred Stock is exchangeable for one share of Series B-2 Voting Preferred Stock, except as otherwise provided in the Amended and Restated Certificate of Designations, Preferences and Rights.</footnote>
    </footnotes>

    <remarks>Eastern Capital Limited is an investment entity that owns the securities reported on this Form 3.  Portfolio Services Ltd. is a holding company which owns all of the outstanding stock of Eastern Capital Limited. Kenneth B. Dart is the beneficial owner of all of the outstanding stock of Portfolio Services Ltd.</remarks>

    <ownerSignature>
        <signatureName>Eastern Capital Limited</signatureName>
        <signatureDate>2013-08-23</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Portfolio Services Limited</signatureName>
        <signatureDate>2013-08-23</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Kenneth B. Dart</signatureName>
        <signatureDate>2013-08-23</signatureDate>
    </ownerSignature>
</ownershipDocument>
