605 15 July 2001 Form 605 Corporations Act 2001 Section 671B Notice of ceasing to be a substantial holder To Company Name/Scheme Rio Tinto Limited ACN/ARSN 004 458 404 1. Details of substantial holder (1) Name Vanguard Group (The Vanguard Group, Inc. and its controlled entities including Vanguard _________Investments Australia Ltd. and those listed in Annexure A) ACN/ARSN (if applicable) N/A The holder ceased to be a substantial holder on 29 November 2021 The previous notice was given to the company on 15 November 2021 The previous notice was dated 15 November 2021 2. Changes in relevant interests Particulars of each change in, or change in the nature of, a relevant interest (2) of the substantial holder or an associate (3) in voting securities of the company or scheme, since the substantial holder was last required to give a substantial holding notice to the company or scheme are as follows: Date of change Person whose relevant interest changed Nature of change (4) Consideration given in relation to change (5) Class (6) and number of securities affected Person's votes affected See Annexure A Vanguard Group now holds 4.930% of voting power 3. Changes in association The persons who have become associates (3) of, ceased to be associates of, or have changed the nature of their association (7) with, the substantial holder in relation to voting interests in the company or scheme are as follows: Name and ACN/ARSN (if applicable) Nature of association N/A N/A 4. Addresses The addresses of persons named in this form are as follows: Name Address Vanguard Group P.O. Box 2600, V26 Valley Forge, PA 19482 USA Signature print name Shawn Acker capacity Compliance Manager sign here date 2 December 2021 EXHIBIT 99.3

Annexure A To Company Rio Tinto Limited ACN/ARSN 004 458 404 Substantial Holder Name Vanguard Group ACN/ARSN N/A Date of change Person whose relevant interest changed Nature of Change(6) Consideration given in relation to change(7) Class Number of securities affected Person's votes affected 12-Nov-21 The Vanguard Group, Inc. BUY 92.46 Ordinary 700 700 12-Nov-21 The Vanguard Group, Inc. BUY 93.31 Ordinary 5,357 5,357 12-Nov-21 The Vanguard Group, Inc. SELL 94.15 Ordinary (151) (151) 17-Nov-21 The Vanguard Group, Inc. BUY 88.91 Ordinary 178 178 17-Nov-21 The Vanguard Group, Inc. BUY 88.91 Ordinary 250 250 17-Nov-21 The Vanguard Group, Inc. BUY 90.00 Ordinary 3,716 3,716 17-Nov-21 The Vanguard Group, Inc. BUY 90.00 Ordinary 3,456 3,456 18-Nov-21 The Vanguard Group, Inc. BUY 89.10 Ordinary 4,312 4,312 19-Nov-21 The Vanguard Group, Inc. BUY 90.25 Ordinary 318 318 19-Nov-21 The Vanguard Group, Inc. BUY 90.25 Ordinary 4,211 4,211 19-Nov-21 The Vanguard Group, Inc. BUY 88.99 Ordinary 6,691 6,691 19-Nov-21 The Vanguard Group, Inc. BUY 89.29 Ordinary 1,955 1,955 19-Nov-21 The Vanguard Group, Inc. BUY 89.29 Ordinary 608 608 22-Nov-21 The Vanguard Group, Inc. BUY 90.78 Ordinary 4,353 4,353 23-Nov-21 The Vanguard Group, Inc. BUY 95.24 Ordinary 1,564 1,564 24-Nov-21 The Vanguard Group, Inc. BUY 95.07 Ordinary 437 437 24-Nov-21 The Vanguard Group, Inc. BUY 94.97 Ordinary 416 416 24-Nov-21 The Vanguard Group, Inc. BUY 94.97 Ordinary 416 416 26-Nov-21 The Vanguard Group, Inc. BUY 94.46 Ordinary 179 179 26-Nov-21 The Vanguard Group, Inc. BUY 93.35 Ordinary 2,737 2,737 26-Nov-21 The Vanguard Group, Inc. BUY 93.35 Ordinary 456 456 29-Nov-21 The Vanguard Group, Inc. BUY 95.77 Ordinary 2,346 2,346 29-Nov-21 The Vanguard Group, Inc. BUY 95.77 Ordinary 627 627 15-Nov-21 Vanguard Investments Australia Ltd. BUY 92.30 Ordinary 2,108 2,108 17-Nov-21 Vanguard Investments Australia Ltd. BUY 88.91 Ordinary 3,816 3,816 17-Nov-21 Vanguard Investments Australia Ltd. BUY 88.91 Ordinary 3,250 3,250 18-Nov-21 Vanguard Investments Australia Ltd. SELL 89.51 Ordinary (1,174) (1,174) 18-Nov-21 Vanguard Investments Australia Ltd. BUY 89.51 Ordinary 7,949 7,949 18-Nov-21 Vanguard Investments Australia Ltd. BUY 89.51 Ordinary 975 975 19-Nov-21 Vanguard Investments Australia Ltd. BUY 90.25 Ordinary 4,459 4,459 23-Nov-21 Vanguard Investments Australia Ltd. BUY 95.13 Ordinary 3,260 3,260 23-Nov-21 Vanguard Investments Australia Ltd. BUY 95.13 Ordinary 1,304 1,304 24-Nov-21 Vanguard Investments Australia Ltd. BUY 95.07 Ordinary 3,912 3,912 25-Nov-21 Vanguard Investments Australia Ltd. IN SPECIE 96.63 Ordinary (96,074) (96,074) 25-Nov-21 Vanguard Investments Australia Ltd. IN SPECIE 96.63 Ordinary (250,251) (250,251) 25-Nov-21 Vanguard Investments Australia Ltd. BUY 96.63 Ordinary 3,190 3,190 26-Nov-21 Vanguard Investments Australia Ltd. BUY 94.46 Ordinary 3,260 3,260 This is Annexure A of 1 page referred to in Form 605, Notice of ceasing to be a substantial holder. Signature: Name: Shawn Acker Capacity: Compliance Manager Date: 2 December 2021 Page 1 of 1