-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, S8QdTOd2/jDEf4bhYwg0lLuXUW7eAiKK01YUJWi94ELdnvQ+j8G4/fAmp/aPDLGy ZsxO0wm3MjhCD+Te1qk91Q== 0001209191-04-014680.txt : 20040305 0001209191-04-014680.hdr.sgml : 20040305 20040305172200 ACCESSION NUMBER: 0001209191-04-014680 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20040304 FILED AS OF DATE: 20040305 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: GIVEN BRUCE D CENTRAL INDEX KEY: 0001219384 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 000-20117 FILM NUMBER: 04652964 MAIL ADDRESS: STREET 1: 6700 WEST LOOP SOUTH STREET 2: SUITE 400 CITY: BELLAIRE STATE: TX ZIP: 77401 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: ENCYSIVE PHARMACEUTICALS INC CENTRAL INDEX KEY: 0000887023 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 133532643 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 6700 WEST LOOP SOUTH STREET 2: 4TH FLOOR CITY: BELLAIRE STATE: TX ZIP: 77401 BUSINESS PHONE: 7137968822 FORMER COMPANY: FORMER CONFORMED NAME: TEXAS BIOTECHNOLOGY CORP /DE/ DATE OF NAME CHANGE: 19930328 4 1 doc4.xml FORM 4 SUBMISSION X0201 4 2004-03-04 0 0000887023 ENCYSIVE PHARMACEUTICALS INC ENCY 0001219384 GIVEN BRUCE D 6700 WEST LOOP SOUTH 4TH FLOOR BELLAIRE TX 77401 1 1 0 0 President & CEO Common Stock 2004-03-04 4 A 0 8799.0000 0 A 214982.0000 D Non-Qualified Stock Option (right to buy) 9.8500 2004-03-04 4 A 0 118750.0000 0 A 2014-03-04 Common Stock 118750.0000 118750.0000 D Options vest in three equal annual installments beginning on the one year anniversary of the grant date. Stephen L. Mueller by Power of Attorney for Bruce D. Given, M.D. 2004-03-05 EX-24.4_34391 3 poa.txt POA DOCUMENT POWER OF ATTORNEY Know all by these presents, that the undersigned hereby constitutes and appoints each of Stephen L. Mueller and Diana LeBlanc, signing singly, the undersigned's true and lawful attorney-in-fact to: (1) execute for and on behalf of the undersigned, in the undersigned's capacity as an officer and/or director of Texas Biotechnology Corporation (the "Company"), Forms 3, 4, and 5 in accordance with section 16(a) of the Securities Exchange Act of 1934 and the rules thereunder; (2) do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute any such Form 3, 4, or 5, complete and execute any amendment or amendments thereto, and timely file such form with the Unitd States Securities and Exchange Commission and any stock exchange or similar authority; and (3) take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in the best interest of, or legally required by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve in such attorney-in-fact's discretion. The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that such attorney-in-fact, or such attorney-in-fact's substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted. The undersigned acknowledges that the foregoing attorneys-in-fact, in serving in such capacity at the request of the undersigned, are not assuming, nor is the Company assuming, any of the undersigned's responsibilities to coomply with Section 16 of the Securities Exchange Act of 1934. This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Forms 3, 4, and 5 with respect to the undersigned's holdings of and transactions in securities issued by the Company, unless earlier revoked by the undersigned in a signed writing delivered to the foregoing attorneys-in-fact. IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 3rd day of September, 2002. /s/ Bruce D. Given, M.D. Signature Bruce D. Given, M.D. Print Name -----END PRIVACY-ENHANCED MESSAGE-----