EX-12.1 4 h25685exv12w1.htm COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES exv12w1
 

EXHIBIT 12.1

ENCYSIVE PHARMACEUTICALS INC.
STATEMENT REGARDING THE COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES
(in thousands)

                                                 
    Three Months        
    Ended     Year Ended December 31,  
    March 31, 2005     2004     2003     2002     2001     2000  
 
Income (loss) before income taxes
   $ (17,709 )   $ (55,415 )   $ (36,518 )   $ (24,686 )   $ (19,891 )   $ (3,498 )
 
Add fixed charges Interest expense
     199       143       152       8       —       —  
 
                                    
Subtotal fixed charges
     199       143       152       8       —       —  
 
                                    
 
Total income (loss) before income taxes and fixed charges
   $ (17,510 )   $ (55,272 )   $ (36,366 )   $ (24,678 )   $ (19,891 )   $ (3,498 )
 
                                    
 
Ratio of fixed charges to income (loss) before income taxes and fixed charges1
     na       na       na       na       na       na  
 
                                    

1        Earnings were inadequate to cover fixed charges by $17.5 million in the three months ended March 31, 2005, and $55.3 million, $36.4 million, $24.7 million, $19.9 million and $3.5 million in the years ended December 31, 2004, 2003, 2002, 2001 and 2000, respectively.