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Proc-Type: 2001,MIC-CLEAR
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<SEC-DOCUMENT>0000950129-04-005384.txt : 20040802
<SEC-HEADER>0000950129-04-005384.hdr.sgml : 20040802
<ACCEPTANCE-DATETIME>20040802112914
ACCESSION NUMBER:		0000950129-04-005384
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20040802
ITEM INFORMATION:		Other events
FILED AS OF DATE:		20040802

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ENCYSIVE PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0000887023
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				133532643
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-20117
		FILM NUMBER:		04944153

	BUSINESS ADDRESS:	
		STREET 1:		6700 WEST LOOP SOUTH
		STREET 2:		4TH FLOOR
		CITY:			BELLAIRE
		STATE:			TX
		ZIP:			77401
		BUSINESS PHONE:		7137968822

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	TEXAS BIOTECHNOLOGY CORP /DE/
		DATE OF NAME CHANGE:	19930328
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>h17211e8vk.txt
<DESCRIPTION>ENCYSIVE PHARMACEUTICALS INC. - DATED 8/2/2004
<TEXT>
<PAGE>
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                    FORM 8-K


                                 CURRENT REPORT

                       Pursuant to Section 13 or 15 (d) of
                       the Securities Exchange Act of 1934


        Date of Report (Date of earliest event reported): August 2, 2004


                          ENCYSIVE PHARMACEUTICALS INC.
             (Exact name of registrant as specified in its charter)


<Table>
<S>                           <C>                           <C>
       DELAWARE                       0-20117                           13-3532643
(State of Incorporation)      (Commission File Number)      (IRS Employer Identification No.)
</Table>


                            6700 WEST LOOP, 4TH FLOOR
                              BELLAIRE, TEXAS 77401
              (Address of Registrant's principal executive offices)

                                 (713) 796-8822
              (Registrant's telephone number, including area code)


                                 Not Applicable
          (Former name or former address, if changed since last report)


<PAGE>


ITEM 5. OTHER EVENTS AND REGULATION FD DISCLOSURE

         On August 2, 2004, Encysive Pharmaceuticals Inc. issued a press release
announcing that that William R. Ringo resigned from the Company's Board of
Directors following his appointment as Chief Executive Officer of Abgenix, Inc.
Mr. Ringo has served as a member of the Board since October of 2001. His
departure reduces the number of directors to 10.


                            [SIGNATURE PAGE FOLLOWS]


<PAGE>


                                    SIGNATURE


         Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its behalf by the
undersigned hereunto duly authorized.


                                      Encysive Pharmaceuticals Inc.

Date: August 2, 2004              By: /s/ Stephen L. Mueller
                                      ----------------------
                                      Stephen L. Mueller
                                      Vice-President, Finance and Administration
                                      Secretary and Treasurer


</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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