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STATEMENTS OF OPERATIONS - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Revenues:      
License fees and royalties $ 1,393 $ 253 $ 460
Operating expenses:      
Research and development 85,727 51,488 52,072
General and administrative 29,665 25,678 20,893
Total operating expenses 115,392 77,166 72,965
Loss from operations (113,999) (76,913) (72,505)
Interest income 527 1,828 4,221
Interest expense (3,740) (760)  
Change in fair value of equity investment   60 (195)
Other income and (expense), net 1,100 168 (69)
Net loss $ (116,112) $ (75,617) $ (68,548)
Basic and diluted net loss per share $ (0.35) $ (0.28) $ (0.36)
Shares used in computing basic and diluted net loss per share 327,631,814 271,460,265 190,160,311