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CONDENSED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Cash flows from operating activities:    
Net loss $ (32,179) $ (24,298)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 60 26
Accretion and amortization on investments, net (34) (958)
Gain on sale of available for sale securities (19)  
Change in fair value of equity investment, including foreign currency translation (279) 3
Stock-based compensation for services by non-employees 32 33
Stock-based compensation for employees and directors 3,275 2,860
Amortization related to 401(k) contributions   9
Amortization of right-of-use assets 580 334
Changes in assets and liabilities:    
Current and noncurrent assets 389 (386)
Amount due to Janssen Biotech, Inc. (14,269) (1,034)
Other current and noncurrent liabilities 3,855 1,928
Net cash used in operating activities (38,589) (21,483)
Cash flows from investing activities:    
Purchases of property and equipment (386) (67)
Purchases of marketable securities (182,355) (66,408)
Proceeds from sales of securities available for sale 7,681  
Proceeds from maturities of marketable securities 78,012 94,851
Net cash (used in) provided by investing activities (97,048) 28,376
Cash flows from financing activities:    
Proceeds from issuance of common stock from equity plans 82  
Proceeds from issuance of common stock and warrants in public offering, net of paid issuance costs 140,794  
Proceeds from issuances of common stock from at market offerings, net of paid issuance costs 4,075 243
Net cash provided by financing activities 144,951 243
Net increase in cash, cash equivalents and restricted cash 9,314 7,136
Cash, cash equivalents and restricted cash at the beginning of the period 13,914 10,844
Cash, cash equivalents and restricted cash at the end of the period $ 23,228 $ 17,980