Basis of Presentation and Summary of Significant Accounting Policies (Tables)

12 Months Ended

Dec. 31, 2019

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Schedule of Major Customers

Revenue from significant partners, which is defined as 10% or more of our total revenue, was as follows:

	December 31,
	2019		2018		2017
Partner A	13	%	40	%	46	%
Partner B	27	%	13	%	19	%
Partner C	< 10%		20	%	< 10%

Schedule of Commercial License Rights

Commercial license and other economic rights consist of the following (in thousands):

	As of December 31,
	2019		2018
Aziyo & CorMatrix	$	17,696	$	17,696
Palvella	10,000		10,000
Selexis	8,602		8,602
Dianomi	2,000		—
	38,298		36,298
Less: accumulated amortization attributed to principal or research and development	(18,208)		(4,838)
Total commercial license and other economic rights, net	$	20,090	$	31,460

Schedule of Disaggregation of Revenue

Royalty revenue for 2019, 2018 and 2017 are reported as below (in thousands):

	Year ended December 31,
	2019(1)		2018(1)		2017(2)
Promacta	$	14,193	$	99,260	$	62,918
Kyprolis	25,046		21,686		16,413
Evomela	5,171		5,658		7,155
Other	2,566		1,952		2,199
	$	46,976	$	128,556	$	88,685

(1) Royalty revenue for 2019 and 2018 was reported under the current revenue recognition guidance (ASC 606).

(2) Royalty revenue for 2017 was reported under the legacy revenue recognition guidance (ASC 605).

The following table represents disaggregation of Material Sales and License fees, milestone and other (in thousands), which are not affected by the adoption of ASC 606:

	Year ended December 31,
	2019		2018		2017
Material Sales
Captisol	$	31,489	$	29,123	$	22,070
License fees, milestones and other
License fees	6,199		78,195		13,665
Milestones	23,451		6,577		11,093
Other	12,167		9,002		5,589
	$	41,817	$	93,774	$	30,347

Schedule of Computation of Basic and Diluted Net Income (Loss) per Share

The following table presents the calculation of weighted average shares used to calculate basic and diluted earnings per share (in thousands):

	Year Ended December 31,
	2019	2018	2017
Weighted average shares outstanding:	18,995	21,160	21,032
Dilutive potential common shares:
Restricted stock	43	72	141
Stock options	719	1,125	1,000
Warrants associated with 2019 Notes	—	1,017	94
2019 Convertible Senior Notes	—	693	1,214
Shares used to compute diluted income per share	19,757	24,067	23,481
Potentially dilutive shares excluded from calculation due to anti-dilutive effect	8,926	2,845	335