X0306 4 2022-12-13 0000885725 BOSTON SCIENTIFIC CORP BSX 0001484186 Fitzgerald Joseph Michael 300 BOSTON SCIENTIFIC WAY MARLBOROUGH MA 01752-1234 1 EVP & Group Pres, Cardiology Common Stock 2022-07-29 5 G 0 1000.0000 0.0000 D 216871.0000 D Common Stock 2022-12-13 4 M 0 79264.0000 7.3900 A 296135.0000 D Common Stock 2022-12-13 4 S 0 79264.0000 47.7800 D 216871.0000 D Common Stock 68082.0000 I By 401(k) Common Stock 7428.0000 I By Children Stock Option (Right to Buy) 7.3900 2022-12-13 4 M 0 79264.0000 0.0000 D 2023-02-28 Common Stock 79264.0000 0.0000 D The transactions reported in this Form 4 were effected pursuant to a pre-established Rule 10b5-1 trading plan. Balance reflects the most current data available with regard to share holdings in the Company's 401(k) Retirement Savings Plan. The reporting person disclaims beneficial ownership of the shares held by his children, and this report should not be deemed an admission that the reporting person is the beneficial owner of his children's shares for purposes of Section 16 or for any other purpose. Grant to the reporting person of an option to purchase a specified number of shares of common stock vesting in four equal annual installments beginning on February 28, 2014, the first anniversary of the date of grant. /s/ Susan Thompson, Attorney-in-Fact 2022-12-13