X0306 4 2021-07-27 0000885725 BOSTON SCIENTIFIC CORP BSX 0001801586 Scanlon Meghan 300 BOSTON SCIENTIFIC WAY MARLBOROUGH MA 01752-1234 1 SVP,Pres,Urology Pelvic Health Common Stock 2021-07-27 4 M 0 13850.0000 23.4100 A 32992.0000 D Common Stock 2021-07-27 4 S 0 13850.0000 45.0100 D 19142.0000 D Stock Option (Right to Buy) 23.4100 2021-07-27 4 M 0 13850.0000 0.0000 D 2026-07-01 Common Stock 13850.0000 0.0000 D The transactions reported in this Form 4 were effected pursuant to a pre-established Rule 10b5-1 trading plan. Includes shares acquired under the Boston Scientific Global Employee Stock Purchase Plan based upon the most current data available. Represents the weighted average sale price. These shares were sold in multiple transactions at $45.00 and $45.02. The reporting person undertakes to provide upon request by the U.S. Securities and Exchange Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price. Grant to the reporting person of an option to purchase 13,850 shares of common stock vesting in four equal annual installments beginning on July 1, 2017, the first anniversaryof the date of grant. /s/ Vance R. Brown, Attorney-in-fact 2021-07-27