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Hedging Activities and Fair Value Measurements - 1 (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Derivative assets $ 79 $ 107  
Derivative Liability, Statement of Financial Position [Extensible Enumeration] Other Liabilities, Noncurrent    
Fair value of contingent consideration $ 171 404 $ 149
Cash 364 411  
Debt Instrument, Fair Value Disclosure $ 10,330 8,735  
Financial Asset      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Risk-Adjusted Discount Rates used in Purchase Price Allocation 15.00%    
Level 3      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Licensing arrangements $ 24    
Licensing arrangements 33    
Fair Value, Measurements, Recurring [Member]      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Money Market Funds, at Carrying Value 120 454  
Equity Securities, FV-NI 19 18  
Derivative assets 384 266  
Licensing arrangements 24 77  
Assets, Fair Value Disclosure 547 816  
Foreign Currency Contracts, Liability, Fair Value Disclosure 990 1,050  
Fair value of contingent consideration 171 404  
Licensing arrangements 33 90  
Financial and Nonfinancial Liabilities, Fair Value Disclosure 1,194 1,545  
Fair Value, Measurements, Recurring [Member] | Level 1      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Money Market Funds, at Carrying Value 120 454  
Equity Securities, FV-NI 19 18  
Derivative assets 0 0  
Licensing arrangements 0 0  
Assets, Fair Value Disclosure 139 472  
Foreign Currency Contracts, Liability, Fair Value Disclosure 0 0  
Fair value of contingent consideration 0 0  
Licensing arrangements 0 0  
Financial and Nonfinancial Liabilities, Fair Value Disclosure 0 0  
Fair Value, Measurements, Recurring [Member] | Level 2      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Money Market Funds, at Carrying Value 0 0  
Equity Securities, FV-NI 0 0  
Derivative assets 384 266  
Licensing arrangements 0 0  
Assets, Fair Value Disclosure 384 266  
Foreign Currency Contracts, Liability, Fair Value Disclosure 990 1,050  
Fair value of contingent consideration 0 0  
Licensing arrangements 0 0  
Financial and Nonfinancial Liabilities, Fair Value Disclosure 990 1,050  
Fair Value, Measurements, Recurring [Member] | Level 3      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Money Market Funds, at Carrying Value 0 0  
Equity Securities, FV-NI 0 0  
Derivative assets 0 0  
Licensing arrangements 24 77  
Assets, Fair Value Disclosure 24 77  
Foreign Currency Contracts, Liability, Fair Value Disclosure 0 0  
Fair value of contingent consideration 171 404  
Licensing arrangements 33 90  
Financial and Nonfinancial Liabilities, Fair Value Disclosure 203 494  
Fair Value, Measurements, Recurring [Member] | Level 3 | Financial Asset      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Licensing arrangements 24 77 127
Proceeds from Royalties Received (40) (61)  
Increase (Decrease) in Fair Value Adjustments on Other Assets (Liabilities) Carried at Fair Value under Fair Value Option (13) 11  
Fair Value, Measurements, Recurring [Member] | Level 3 | Financial Liability      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Licensing arrangements 33 90 $ 159
Payments for Royalties (45) (80)  
Increase (Decrease) in Fair Value Adjustments on Other Assets (Liabilities) Carried at Fair Value under Fair Value Option $ (12) $ 12  
Minimum | Financial Liability      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Risk-Adjusted Discount Rates used in Purchase Price Allocation 12.00%    
Maximum      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Fair value of contingent consideration $ 220    
Maximum | Financial Liability      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Risk-Adjusted Discount Rates used in Purchase Price Allocation 15.00%    
Weighted Average | Financial Asset      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Risk-Adjusted Discount Rates used in Purchase Price Allocation 15.00%    
Weighted Average | Financial Liability      
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]      
Risk-Adjusted Discount Rates used in Purchase Price Allocation 13.00%