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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2023
Income Tax Disclosure [Abstract]  
Schedule of Income before Income Tax, Domestic and Foreign
Our Income (loss) before income taxes consisted of the following:
Year Ended December 31,
(in millions)202320222021
Domestic$(394)$(1,119)$(648)
Foreign2,379 2,260 1,724 
$1,985 $1,141 $1,076 
Schedule of Components of Income Tax Expense (Benefit)
The related expense (benefit) for income taxes consisted of the following:
Year Ended December 31,
(in millions)202320222021
Current
Federal$189 $51 $18 
State15 19 33 
Foreign116 381 127 
320 451 178 
Deferred
Federal(82)(92)(256)
State(22)(32)(3)
Foreign176 117 117 
73 (7)(142)
$393 $443 $36 
Schedule of Deferred Tax Assets and Liabilities
Significant components of our deferred tax assets and liabilities are as follows:
 As of December 31,
 (in millions)
20232022
 Deferred Tax Assets:
 
Inventory costs and related reserves$30 $19 
Tax benefit of net operating losses and credits744 511 
Reserves and accruals305 304 
Restructuring-related charges14 
Litigation and product liability reserves88 103 
Investment write-down58 38 
Compensation related154 136 
Federal benefit of uncertain tax positions11 
Intangible assets3,394 3,668 
Capitalized R&D232 160 
Property, plant and equipment— 
 5,029 4,954 
Less: valuation allowance(1,220)(1,004)
 3,809 3,950 
 Deferred Tax Liabilities:
  
Property, plant and equipment24 — 
Unrealized gains and losses on derivative financial instruments66 117 
Other12 34 
102 151 
 Net Deferred Tax Assets
3,707 3,799 
Prepaid on intercompany profit315 264 
 Net Deferred Tax Assets and Prepaid on Intercompany Profit$4,022 $4,062 

Our deferred tax assets, deferred tax liabilities and prepaid on intercompany profit are included in the following locations within our accompanying consolidated balance sheets (in millions):
Location on Consolidated Balance SheetsAs of December 31,
Component20232022
Prepaid on intercompany profitPrepaid income taxes$315 $264 
Non-current deferred tax assetDeferred tax assets3,841 3,942 
Deferred Tax Assets and Prepaid on Intercompany Profit 4,157 4,206 
Non-current deferred tax liabilityDeferred tax liabilities134 144 
Deferred Tax Liabilities 134 144 
Net Deferred Tax Assets and Prepaid on Intercompany Profit$4,022 $4,062 
Summary of Income Tax Contingencies A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows:
 Year Ended December 31,
(in millions)202320222021
Beginning Balance$492 $255 $261 
Additions based on positions related to the current year65 88 
Additions based on positions related to prior years67 177 41 
Reductions for tax positions of prior years(114)(20)(36)
Settlements with taxing authorities(14)(1)(2)
Statute of limitation expirations(29)(8)(17)
Ending Balance$467 $492 $255 
Tax rate
The reconciliation of income taxes at the federal statutory rate to the actual expense (benefit) for income taxes is as follows:
Year Ended December 31,
202320222021
U.S. federal statutory income tax rate21.0 %21.0 %21.0 %
State income taxes, net of federal benefit0.7 %0.7 %2.5 %
Domestic taxes on foreign earnings6.9 %15.3 %6.8 %
Effect of foreign taxes(15.3)%(3.8)%(14.3)%
Acquisition-related2.2 %4.4 %(8.1)%
Research credit(2.9)%(4.5)%(3.0)%
Valuation allowance7.5 %(1.3)%0.8 %
Compensation-related0.5 %0.6 %(0.6)%
Non-deductible expenses0.4 %0.4 %0.4 %
Uncertain tax positions(0.5)%7.7 %1.2 %
Return to provision(0.1)%(2.1)%(5.7)%
Change in tax rates(0.6)%(0.2)%1.9 %
Other, net— %0.7 %0.4 %
19.8 %38.9 %3.3 %