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Supplemental Balance Sheet Information (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Dec. 31, 2020
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Line Items]            
Cash and Cash Equivalents $ 276 $ 2,675 $ 276 $ 2,675 $ 1,925  
Restricted Cash and Cash Equivalents in Other current assets 132 167 132 167 188  
Restricted Cash Equivalents in Other long-term assets 50 57 50 57 55  
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents 458 2,898 458 2,898 2,168 $ 1,995
Depreciation 80 83 156 166    
Trade accounts receivable, net            
Accounts receivable 2,034   2,034   1,886  
Less: allowance for doubtful accounts (117)   (117)   (108)  
Trade accounts receivable, net 1,917   1,917   1,778  
Allowance for doubtful accounts            
Beginning balance 113 101 108 105    
Charges to expenses 9 9 20 11    
Utilization of allowances (5) (4) (11) (10)    
Ending balance 117 107 117 107    
Inventories            
Inventory, Finished Goods, Net of Reserves 1,082   1,082   1,029  
Inventory, Work in Process, Net of Reserves 144   144   128  
Inventory, Raw Materials, Net of Reserves 526   526   452  
Inventories 1,752   1,752   1,610  
Other Current Assets [Abstract]            
Restricted Cash and Cash Equivalents in Other current assets 132 167 132 167 188  
Derivative Asset, Current 286   286   226  
Licensing arrangements 94   94   132  
Other Assets, Miscellaneous, Current 362   362   254  
Other Assets, Current 874   874   799  
Property, plant and equipment, net            
Land 118   118   109  
Buildings and improvements 1,406   1,406   1,335  
Equipment, furniture and fixtures 3,453   3,453   3,475  
Capital in progress 537   537   605  
Property, plant and equipment 5,514   5,514   5,525  
Less: accumulated depreciation 3,268   3,268   3,273  
Property, plant and equipment, net 2,246   2,246   2,252  
Supplemental Balance Sheet Information            
Depreciation expense 80 83 156 166    
Other Assets, Noncurrent [Abstract]            
Restricted cash equivalents included in Other long-term assets 50 $ 57 50 $ 57 55  
Operating Lease, Right-of-Use Asset 400   400   435  
Derivative Asset 252   252   169  
Investments 384   384   412  
Licensing arrangements, asset 88   88   114  
Indemnification asset 163   163   0  
Other, Other Long-term Assets 230   230   225  
Other Assets, Noncurrent 1,569   1,569   1,410  
Accrued expenses            
Legal reserves, current 359   359   264  
Payroll and related liabilities 754   754   848  
Accrued Rebates, Current 335   335   350  
Business Combination, Contingent Consideration, Liability, Current 133   133   289  
Other 615   615   686  
Accrued Liabilities, Current 2,197   2,197   2,436  
Other Liabilities, Current [Abstract]            
Deferred Revenue, Current 222   222   208  
Accrued Royalties, Current 112   112   138  
Taxes Payable, Current 257   257   209  
Other Sundry Liabilities, Current 193   193   228  
Other Liabilities, Current 784   784   783  
Other long-term liabilities            
Accrued income taxes 550   550   442  
Estimated Litigation Liability, Noncurrent 155   155   284  
Business Combination, Contingent Consideration, Liability, Noncurrent 86   86   197  
Licensing arrangements, liability 103   103   143  
Operating Lease, Liability, Noncurrent 357   357   389  
Deferred Revenue 279   279   276  
Other Accrued Liabilities, Noncurrent 458   458   489  
Other long-term liabilities $ 1,988   $ 1,988   $ 2,220