<SEC-DOCUMENT>0001193125-17-350581-index.html : 20171122
<SEC-HEADER>0001193125-17-350581.hdr.sgml : 20171122
<ACCEPTANCE-DATETIME>20171122144500
ACCESSION NUMBER:		0001193125-17-350581
CONFORMED SUBMISSION TYPE:	424B5
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20171122
DATE AS OF CHANGE:		20171122

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Express Scripts Holding Co.
		CENTRAL INDEX KEY:			0001532063
		STANDARD INDUSTRIAL CLASSIFICATION:	RETAIL-DRUG STORES AND PROPRIETARY STORES [5912]
		IRS NUMBER:				452884094
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-221565
		FILM NUMBER:		171219674

	BUSINESS ADDRESS:	
		STREET 1:		ONE EXPRESS WAY
		CITY:			ST. LOUIS
		STATE:			MO
		ZIP:			63121
		BUSINESS PHONE:		314-996-0900

	MAIL ADDRESS:	
		STREET 1:		ONE EXPRESS WAY
		CITY:			ST. LOUIS
		STATE:			MO
		ZIP:			63121

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Aristotle Holding, Inc.
		DATE OF NAME CHANGE:	20111005

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MEDCO HEALTH SOLUTIONS INC
		CENTRAL INDEX KEY:			0001170650
		STANDARD INDUSTRIAL CLASSIFICATION:	RETAIL-DRUG STORES AND PROPRIETARY STORES [5912]
		IRS NUMBER:				223461740
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-221565-02
		FILM NUMBER:		171219675

	BUSINESS ADDRESS:	
		STREET 1:		100 PARSONS POND DR
		CITY:			FRANKLIN LAKES
		STATE:			NJ
		ZIP:			07417
		BUSINESS PHONE:		2012693400

	MAIL ADDRESS:	
		STREET 1:		100 PARSONS POND DR
		CITY:			FRANKLIN LAKES
		STATE:			NJ
		ZIP:			07417

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MEDCOHEALTH SOLUTIONS INC
		DATE OF NAME CHANGE:	20020528

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MERCK MEDCO MANAGED CARE LLC
		DATE OF NAME CHANGE:	20020404

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			EXPRESS SCRIPTS INC
		CENTRAL INDEX KEY:			0000885721
		STANDARD INDUSTRIAL CLASSIFICATION:	RETAIL-DRUG STORES AND PROPRIETARY STORES [5912]
		IRS NUMBER:				431420563
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B5
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-221565-01
		FILM NUMBER:		171219676

	BUSINESS ADDRESS:	
		STREET 1:		ONE EXPRESS WAY
		CITY:			ST LOUIS
		STATE:			MO
		ZIP:			63121
		BUSINESS PHONE:		3149960900

	MAIL ADDRESS:	
		STREET 1:		ONE EXPRESS WAY
		CITY:			ST LOUIS
		STATE:			MO
		ZIP:			63121
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B5
<SEQUENCE>1
<FILENAME>d483480d424b5.htm
<DESCRIPTION>424B5
<TEXT>
Document 1 - file: d483480d424b5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>g483480g88u05.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: g483480g88u05.jpg

</DOCUMENT>
</SEC-DOCUMENT>