CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Per Share data	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
License and collaboration revenue	$ 39	$ 172,256	$ 39	$ 174,410
Service revenue	27	2,793	83	2,793
Total revenue	66	175,049	122	177,203
Operating expenses:
Research and development	18,754	13,814	33,329	28,649
General and administrative	6,152	4,001	11,005	8,575
Total operating expenses	24,906	17,815	44,334	37,224
Income (loss) from operations	(24,840)	157,234	(44,212)	139,979
Other income (expense):
Interest income	44	14	99	22
Interest expense	(63)	(38)	(123)	(109)
Revaluation of warrant liability	(22,903)	2,138	(41,475)	(3,942)
Other income (expense), net	(22,922)	2,114	(41,499)	(4,029)
Net income (loss)	$ (47,762)	$ 159,348	$ (85,711)	$ 135,950
Net income (loss) per share - basic	$ (0.36)	$ 1.44	$ (0.66)	$ 1.24
- diluted	$ (0.36)	$ 1.35	$ (0.66)	$ 1.22
Weighted-average number of shares of common stock outstanding - basic	132,021	110,290	130,518	109,657
- diluted	132,021	116,079	130,518	114,373