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Fair Value Measurements and Investments - Schedule of Change in Valuation of Securities (Detail) - Bone Biologics Inc [Member] - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]        
Equity securities and warrants beginning balance $ 219 $ 4,668 $ 219 $ 2,768
Purchase of additional common stock 0 0 0 500
Fair value adjustments, expirations, and impairments recognized in other income (expense), net 0 (4,449) 0 (4,678)
Equity securities and warrants ending balance 219 219 219 219
ASU 2016-01 [Member]        
Fair Value Assets Measured On Recurring Basis Unobservable Input Reconciliation [Line Items]        
Impact of adoption of ASU 2016-01 recognized in other income (expense), net $ 0 $ 0 $ 0 $ 1,629