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Summary of significant accounting policies (Details 6) (USD $)
In Millions, unless otherwise specified
12 Months Ended 1 Months Ended 12 Months Ended
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Jan. 31, 2012
Collaborative arrangements
Musculoskeletal Transplant Foundation ("MTF")
Y
Dec. 31, 2009
Collaborative arrangements
Musculoskeletal Transplant Foundation ("MTF")
Y
Summary of significant accounting policies          
Period of agreement with MTF (in years)         10
Extended Period of existing agreement with MTF (in years)       5  
Advertising expense $ 0.5 $ 0.6 $ 0.7    
Income taxes          
Unrecognized tax benefits inclusive of interest and penalties $ 1.2 $ 1.0