X0206 3 2022-01-06 0 0000883984 ICU MEDICAL INC/DE ICUI 0001326143 SMITHS GROUP PLC 11-12 ST JAMES'S SQUARE 4TH FLOOR LONDON X0 SW1Y 4LB UNITED KINGDOM 0 0 1 0 Common Stock 2500000 I Smiths Group International Holdings Limited These shares are held directly by Smiths Group International Holdings Limited ("SGIH"). SGIH is a wholly owned subsidiary of Smiths Group plc ("SGP"). SGP is an indirect beneficial owner of the shares. Reporting Owner Name/Address/Relationship to Issuer: Smiths Group plc (SGP), 4th Floor, 11-12 St James's Square, London, England SW1Y 4LB; 10% Ownership; Smiths Group International Holdings Limited (SGIH), 4th Floor, 11-12 St James's Square, London, England SW1Y 4LB; 10% Ownership. /s/ Smiths Groups plc, Matthew John Whyte, Attorney-in-Fact 2022-01-24