Derivative Warrant Liabilities - Schedule of Outstanding Warrants Liabilities (Details) - $ / shares		12 Months Ended
		Dec. 31, 2018	Dec. 31, 2017
Series A (2013) [Member]
Number of Warrant Outstanding, shares	[1]		3,895
Warrant Exercise Price, Per Share	[1]
Warrant Exercisable	[1]
Number of Warrant Exercisable, Period	[1]	October 2018
Series A (2013) [Member]
Number of Warrant Outstanding, shares	[1]	183	183
Warrant Exercise Price, Per Share	[1]	$ 2,725
Warrant Exercisable	[1]	183
Number of Warrant Exercisable, Period	[1]	April 2023
Series A (2015) [Member]
Number of Warrant Outstanding, shares	[1]	683	683
Warrant Exercise Price, Per Share	[1]	$ 1,363
Warrant Exercisable	[1]	683
Number of Warrant Exercisable, Period	[1]	April 2020
Series A (2016) [Member]
Number of Warrant Outstanding, shares	[1],[2]		625
Warrant Exercise Price, Per Share	[1],[2]
Warrant Exercisable	[1],[2]
Number of Warrant Exercisable, Period	[1],[2]	March 2018
Series B (2016) [Member]
Number of Warrant Outstanding, shares	[1],[2]	2,770	2,770
Warrant Exercise Price, Per Share	[1],[2]	$ 40
Warrant Exercisable	[1],[2]	2,770
Number of Warrant Exercisable, Period	[1],[2]	March 2022

[1] December 31, 2018 and 2017 warrant data represents the number of shares adjusted to retroactively reflect the 1:15 Reverse Split effected on September 4, 2018. Refer to Note 1 for further information.

[2] These warrants contain a full ratchet anti-dilution price protection so that, in most situations upon the issuance of any common stock or securities convertible into common stock at a price below the then-existing exercise price of the outstanding warrants, the warrant exercise price will be reset to the lower common stock sales price. As such anti-dilution price protection does not meet the specific conditions for equity classification, the Company is required to classify the fair value of these warrants as a liability, with changes in fair value to be recorded as income (loss) due to change in fair value of warrant liability. The estimated fair value of the Company's warrant liability at December 31, 2018 and December 31, 2017, was approximately $8 and $28, respectively.