Consolidated Statements of Comprehensive Income (Loss) - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Revenues:
Total revenues	$ 874,837	$ 450,712	$ 331,412
Expenses:
Cost of product sales	19,075	12,269	4,481
Research and development	166,126	174,638	216,566
Selling, general and administrative	348,647	266,348	214,074
Total operating expenses	533,848	453,255	435,121
Income (loss) from operations	340,989	(2,543)	(103,709)
Other income (expense):
Interest income	10,668	14,746	15,777
Interest expense	(78,872)	(98,516)	(108,239)
Foreign currency losses, net	(152)	(641)	(1,039)
Loss on extinguishment of debt	(17,332)	0	(29,019)
Other income	12,090	0	0
Total other expense, net	(73,598)	(84,411)	(122,520)
Income (loss) before income taxes	267,391	(86,954)	(226,229)
Income tax expense	3,530	1,927	310
Net income (loss)	263,861	(88,881)	(226,539)
Other comprehensive income (loss):
Foreign currency translation adjustment	(674)	(776)	180
Unrealized (loss) gain on available for sale investments	(209)	360	1,131
Total other comprehensive (loss) income	(883)	(416)	1,311
Net comprehensive income (loss)	$ 262,978	$ (89,297)	$ (225,228)
Net income (loss) per common share: basic (in usd per share)	$ 1.26	$ (0.43)	$ (1.18)
Weighted average shares of common stock outstanding: basic (in shares)	209,893	206,696	192,198
Net income (loss) per common share: diluted (in usd per share)	$ 1.21	$ (0.43)	$ (1.18)
Weighted average shares of common stock outstanding: diluted (in shares)	218,581	206,696	192,198
Product sales, net
Revenues:
Total revenues	$ 623,151	$ 442,668	$ 324,696
License and other revenues
Revenues:
Total revenues	$ 251,686	$ 8,044	$ 6,716