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Collaborative and Other Relationships Textual (Details)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Nov. 03, 2023
USD ($)
payment
Nov. 05, 2019
USD ($)
Sep. 30, 2024
USD ($)
dose
period
Sep. 30, 2018
USD ($)
dose
Dec. 31, 2024
dose
Sep. 29, 2025
dose
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
dose
Dec. 31, 2021
USD ($)
dose
Dec. 31, 2019
USD ($)
dose
Nov. 30, 2023
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
Revenues             $ 450,712 $ 331,412 $ 270,827      
Torii Pharmaceutical Co                        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
Contract with customer, liability   $ 22,000                    
Potential milestone payments receivable if regulatory approval before december 31, 2021   $ 15,000                    
Maximum customary reduction on royalty rate   50.00%                    
Royalty payments receivable, expiration term from first commercial (year)   10 years                    
Torii Pharmaceutical Co | Minimum                        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
Royalty rate if maintains sakigake designation   20.00%                   20.00%
Torii Pharmaceutical Co | Maximum                        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
Royalty rate if maintains sakigake designation   40.00%                   80.00%
HHS Office of the Administration for Strategic Preparedness and Response                        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
Collaborative agreement contract value     $ 69,388                  
Contract term (year)     5 years                  
HHS Office of the Administration for Strategic Preparedness and Response | RAPIVAB                        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
Maximum number of products, doses | dose     95,600                  
Contract term (year)     12 months                  
Number of optional ordering periods | period     4                  
Proceeds from collaborators     $ 13,878                  
Number of product delivered, doses | dose         2,300              
Revenues             $ 1,672          
HHS Office of the Administration for Strategic Preparedness and Response | RAPIVAB | Forecast                        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
Number of product delivered, doses | dose           19,100            
US Department Of Health And Human Services                        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
Collaborative agreement contract value       $ 34,660                
Contract term (year)       5 years                
US Department Of Health And Human Services | RAPIVAB                        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
Maximum number of products, doses | dose       50,000                
Proceeds from collaborators                 $ 13,864 $ 6,918 $ 13,864  
Number of product delivered, doses | dose                 49,980   20,000  
Number of additional products, doses | dose                 20,000 9,980    
Clearside Biomedical, Inc.                        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
License agreement, upfront payment $ 5,000                      
Number of milestone payments | payment 3                      
Royalty payment, number of tiers | payment 3                      
Clearside Biomedical, Inc. | Annual Net Sales Of $2 Million                        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
Annual global net sales $ 2,000,000                      
Clearside Biomedical, Inc. | Annual Net Sales Greater Than $1.5 Million                        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
Annual global net sales 1,500,000                      
Clearside Biomedical, Inc. | Maximum                        
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]                        
Potential milestone payments payable 30,000                      
Potential milestone payments payable if regulatory approval before milestone $ 47,500