Consolidated Statements of Stockholders' Deficit - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-In Capital	Accumulated Other Comprehensive Income	Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2021		184,350,000
Beginning balance at Dec. 31, 2021	$ (106,986)	$ 1,843	$ 1,098,498	$ 177	$ (1,207,504)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(247,116)				(247,116)
Other comprehensive income (loss)	(151)			(151)
Exercise of stock options, net (in shares)		2,573,000
Exercise of stock options, net	11,900	$ 26	11,874
Vesting of restricted stock units (in shares)		439,000
Vesting of restricted stock units	$ 0	$ 4	(4)
Employee stock purchase plan sales (in shares)	260,000	260,000
Employee stock purchase plan sales, net	$ 2,862	$ 3	2,859
Exercise of warrants (in shares)		253,000
Exercise of warrants	3	$ 3
Issuance of shares to directors in lieu of cash retainer (in shares)		31,000
Issuance of shares to directors in lieu of cash retainer	190		190
Stock-based compensation expense	44,701		44,701
Ending balance (in shares) at Dec. 31, 2022		187,906,000
Ending balance at Dec. 31, 2022	(294,597)	$ 1,879	1,158,118	26	(1,454,620)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(226,539)				(226,539)
Other comprehensive income (loss)	1,311			1,311
Exercise of stock options, net (in shares)		1,276,000
Exercise of stock options, net	6,114	$ 13	6,101
Vesting of restricted stock units (in shares)		1,276,000
Vesting of restricted stock units	$ 0	$ 13	(13)
Employee stock purchase plan sales (in shares)	338,000	338,000
Employee stock purchase plan sales, net	$ 2,596	$ 4	2,592
Exercise of warrants (in shares)		14,997,000
Exercise of warrants	0	$ 150	(150)
Issuance of shares to directors in lieu of cash retainer (in shares)		37,000
Issuance of shares to directors in lieu of cash retainer	342		342
Stock-based compensation expense	55,615		55,615
Shares withheld for taxes for vesting of restricted stock units (in shares)		(59,000)
Shares withheld for taxes for vesting of restricted stock units	$ (370)	$ (1)	(369)
Ending balance (in shares) at Dec. 31, 2023	205,771,000	205,771,000
Ending balance at Dec. 31, 2023	$ (455,528)	$ 2,058	1,222,236	1,337	(1,681,159)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(88,881)				(88,881)
Other comprehensive income (loss)	(416)			(416)
Exercise of stock options, net (in shares)		548,000
Exercise of stock options, net	2,280	$ 5	2,275
Vesting of restricted stock units (in shares)		1,902,000
Vesting of restricted stock units	$ 0	$ 19	(19)
Employee stock purchase plan sales (in shares)	412,000	412,000
Employee stock purchase plan sales, net	$ 1,853	$ 4	1,849
Issuance of shares to directors in lieu of cash retainer (in shares)		4,000
Issuance of shares to directors in lieu of cash retainer	34		34
Stock-based compensation expense	65,413		65,413
Shares withheld for taxes for vesting of restricted stock units (in shares)		(94,000)
Shares withheld for taxes for vesting of restricted stock units	$ (689)	$ (1)	(688)
Ending balance (in shares) at Dec. 31, 2024	208,543,000	208,543,000
Ending balance at Dec. 31, 2024	$ (475,934)	$ 2,085	$ 1,291,100	$ 921	$ (1,770,040)