Revenue - Summary of Revenues (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Disaggregation of Revenue [Line Items]
Revenues	$ 450,712	$ 331,412	$ 270,827
Revenues
Disaggregation of Revenue [Line Items]
Revenues	442,668	324,696	267,710
Revenues | Geographic Distribution, Domestic
Disaggregation of Revenue [Line Items]
Revenues	385,961	288,361	226,358
Revenues | Geographic Distribution, Foreign
Disaggregation of Revenue [Line Items]
Revenues	51,699	37,629	25,275
ORLADEYO
Disaggregation of Revenue [Line Items]
Revenues	437,660	325,990	251,633
Other revenues
Disaggregation of Revenue [Line Items]
Revenues	$ 13,052	$ 5,422	$ 19,194