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Significant Accounting Policies and Concentrations of Risk (Tables)
12 Months Ended
Dec. 31, 2024
Accounting Policies [Abstract]  
Summary of Revenues
The Company recorded the following revenues for the years ended December 31, 2024, 2023, and 2022 (in thousands):
Years Ended December 31,
202420232022
Product sales, net$442,668 $324,696 $267,710 
Collaborative and other revenues8,044 6,716 3,117 
Total revenues$450,712 $331,412 $270,827 
The Company recorded the following revenues for the years ended December 31, 2024, 2023, and 2022 (in thousands):
Years Ended December 31,
202420232022
ORLADEYO:
U.S.$385,961 $288,361 $226,358 
Outside of U.S.51,699 37,629 25,275 
Total ORLADEYO437,660 325,990 251,633 
Other revenues13,052 5,422 19,194 
Total revenues$450,712 $331,412 $270,827 
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share The Company excluded the following potential common shares, presented based on amounts outstanding as of December 31, 2024 and 2023, from the computation of diluted net loss per share attributable to common stockholders for the years ended December 31, 2024 and 2023 because including them would have had an anti-dilutive effect:
December 31,
20242023
Outstanding stock options44,240 41,032 
Unvested restricted stock unit awards10,112 6,507 
Total54,352 47,539