Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2024	Mar. 31, 2023
Cash flows from operating activities:
Net loss	$ (35,379)	$ (53,333)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	306	405
Inventory obsolescence	0	236
Stock-based compensation expense	13,652	14,007
Non-cash interest expense on royalty financing obligations and secured term loan and amortization of debt issuance costs	19,440	20,216
Amortization of premium/discount on investments	(3,181)	(1,385)
Changes in operating assets and liabilities:
Receivables	(3,839)	2,019
Inventory	(1,220)	131
Prepaid expenses and other assets	1,106	(2,547)
Accounts payable and accrued expenses	(44,569)	(27,226)
Deferred revenue	0	(35)
Net cash used in operating activities	(53,684)	(47,512)
Cash flows from investing activities:
Acquisitions of property and equipment	(235)	(160)
Purchase of investments	(88,009)	(148,637)
Sales and maturities of investments	117,000	41,688
Net cash provided by (used in) investing activities	28,756	(107,109)
Cash flows from financing activities:
Net proceeds from common stock issued under stock-based compensation plans	1,681	5,077
Net proceeds from common stock issued to directors in lieu of cash retainer	11	0
Withholding taxes paid on stock-based awards	(2,350)	0
Principal payments on finance lease liabilities	(390)	0
Net cash (used in) provided by financing activities	(1,048)	5,077
Effect of exchange rate on cash, cash equivalents, and restricted cash	(340)	(96)
Decrease in cash, cash equivalents and restricted cash	(26,316)	(149,640)
Cash, cash equivalents and restricted cash at beginning of period	112,447	306,239
Cash, cash equivalents and restricted cash at end of period	86,131	156,599
Supplemental Cash Flow Information [Abstract]
Cash paid for interest	4,987	7,142
Cash paid for taxes	186	142
Taxes withheld on stock-based awards included in accrued expenses	$ 1,846	$ 2,128