Significant Accounting Policies and Concentrations of Risk (Tables)

12 Months Ended

Dec. 31, 2023

Accounting Policies [Abstract]

Summary of Revenues

The Company recorded the following revenues for the years ended December 31, 2023, 2022, and 2021 (in thousands):

	Years Ended December 31,
	2023		2022		2021
Product sales, net	324,696		267,710		136,350
Collaborative and other revenues	6,716		3,117		20,820
Total revenues	$	331,412	$	270,827	$	157,170

The Company recorded the following revenues for the years ended December 31 (in thousands):

	Years Ended December 31,
	2023		2022		2021
ORLADEYO:
U.S.	$	288,361	$	226,358	$	117,836
Outside of U.S.	37,629		25,275		4,719
Total ORLADEYO	325,990		251,633		122,555
Other revenues	5,422		19,194		34,615
Total revenues	$	331,412	$	270,827	$	157,170

Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share

The Company excluded the following potential common shares, presented based on amounts outstanding as of December 31, 2023 and 2022, from the computation of diluted net loss per share attributable to common stockholders because including them would have had an anti-dilutive effect:

	December 31,
	2023	2022
Outstanding stock options	41,032	36,520
Unvested restricted stock unit awards	6,507	4,747
Warrants to purchase common stock	—	15,023
Total	47,539	56,290