Consolidated Statements of Stockholders' Deficit - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-In Capital	Accumulated Other Comprehensive Income	Accumulated Deficit
Balance at Dec. 31, 2021	$ (106,986)	$ 1,843	$ 1,098,498	$ 177	$ (1,207,504)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(74,196)				(74,196)
Other comprehensive income	9			9
Employee stock purchase plan sales, net	1,504	1	1,503
Exercise of stock options, net	5,853	12	5,841
Stock-based compensation expense	9,601		9,601
Balance at Mar. 31, 2022	(164,215)	1,856	1,115,443	186	(1,281,700)
Balance at Dec. 31, 2022	(294,597)	1,879	1,158,118	26	(1,454,620)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(53,333)				(53,333)
Other comprehensive income	559			559
Employee stock purchase plan sales, net	1,575	2	1,573
Exercise of stock options, net	3,502	8	3,494
Stock-based compensation expense	14,007		14,007
Balance at Mar. 31, 2023	$ (328,287)	$ 1,889	$ 1,177,192	$ 585	$ (1,507,953)