XML 56 R46.htm IDEA: XBRL DOCUMENT v3.23.1
Stock-based Compensation (Details Textual)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Jan. 31, 2022
shares
Dec. 31, 2014
shares
Mar. 31, 2023
USD ($)
plan
$ / shares
shares
Mar. 31, 2022
$ / shares
shares
Dec. 31, 2022
shares
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Number of plans | plan     3    
Total unrecognized compensation expense related to non-vested stock options and RSU awards | $     $ 139,166    
Compensation cost expected to be recognized for remainder of fiscal year | $     38,098    
Compensation cost expected to be recognized next year | $     46,800    
Compensation cost expected to be recognized year two | $     35,358    
Compensation cost expected to be recognized year three | $     18,689    
Compensation cost expected to be recognized year four | $     $ 221    
Employee stock purchase plan sales, net (in shares)     176,000 115,000  
Share-Based Payment Arrangement, Option | Non-employee Directors          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Award vesting period (in years)     1 year    
Incentive Plan          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Number of common stock shares available for purchase (in shares)     4,595,000   4,206,000
Incentive Plan | Share-Based Payment Arrangement, Option          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Weighted average grant date fair value stock option awards (in dollars per share) | $ / shares     $ 7.47 $ 11.48  
Incentive Plan | Share-Based Payment Arrangement, Option | Maximum          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Stock option awards remaining contractual term (in years)     10 years    
Incentive Plan | Share-Based Payment Arrangement, Option | Vest 25% Each Year Until Fully Vested          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Award vesting rights, percentage     25.00%    
Award vesting period (in years)     4 years    
Incentive Plan | Share-Based Payment Arrangement, Option | Thirty-six Equal Monthly Installments | Non-employee Directors          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Award vesting period (in years)     3 years    
Incentive Plan | Performance Shares | Vest Upon Successful Completion of Specific Development Milestones          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Award vesting rights, percentage   85.00%      
Performance-based stock options issued in period (in shares)   1,250,000      
Incentive Plan | Performance-based Restricted Stock Units          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Award vesting period (in years) 3 years        
Incentive Plan | Performance-based Restricted Stock Units | Vest 25% Each Year Until Fully Vested          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Award vesting rights, percentage 25.00%        
Incentive Plan | Performance-based Restricted Stock Units | Vest Upon Successful Completion of Specific Development Milestones          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Performance-based restricted stock unit awards issued (in shares) 221,000       21
Incentive Plan | Performance-based Restricted Stock Units | Share-Based Payment Arrangement, Tranche One          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Award vesting rights, percentage 50.00%        
Incentive Plan | Restricted Stock Units (RSUs)          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Weighted average grant date fair value (in dollars per share) | $ / shares     $ 10.32 15.49  
Inducement Plan          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Award vesting period (in years)     4 years    
Expiration period (in years)     10 years    
Weighted average grant date fair value stock option awards (in dollars per share) | $ / shares     $ 6.85 11.14  
Number of common stock shares available for purchase (in shares)     513,000   947,000
Inducement Plan | Vest 25% Each Year Until Fully Vested          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Award vesting rights, percentage     25.00%    
Inducement Plan | Share-Based Payment Arrangement, Option          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Expected Dividend Yield     0.00%    
Inducement Plan | Restricted Stock Units (RSUs)          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Weighted average grant date fair value (in dollars per share) | $ / shares     $ 9.64 $ 16.27  
Employee Stock Purchase Plan          
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]          
Number of shares of common stock authorized to be purchased (in shares)     7,975,000    
Number of common stock shares available for purchase (in shares)     5,617,000    
Percentage of salary to purchase common stock, maximum     15.00%    
Percentage of common stock shares, beginning     85.00%    
Percentage of common stock shares, ending     85.00%    
Maximum number of shares per employee (in shares)     3,000    
Maximum number of shares per employee, amount | $     $ 25