Note 8 - Royalty Monetizations - Schedule of Royalty Financing Obligations (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Royalties Monetizations [Line Items]
Long-term debt, total		$ 298,142	$ 122,609
Non-cash Interest expense on Royalty financing obligation	$ 76,482	37,670	2,108
Balance	449,375	124,717
Royalty revenues paid and payable	(24,168)	(11,154)
Deferred financing costs	34
Balance	501,655	449,375	124,717
2020 RPI Royalty Agreement
Royalties Monetizations [Line Items]
Long-term debt, total			122,609
Non-cash Interest expense on Royalty financing obligation	39,994	33,308	2,108
Balance	147,224	124,717
Royalty revenues paid and payable	(22,237)	(10,801)
Balance	$ 164,981	$ 147,224	$ 124,717
Effective interest rate	22.40%	27.30%
2021 RPI Royalty Agreement
Royalties Monetizations [Line Items]
Long-term debt, total		$ 150,833
Non-cash Interest expense on Royalty financing obligation	$ 22,239	2,897
Balance	153,377
Royalty revenues paid and payable	(1,931)	(353)
Deferred financing costs	34
Balance	$ 173,651	$ 153,377
Effective interest rate	13.10%	16.50%
OMERS Royalty Agreement
Royalties Monetizations [Line Items]
Long-term debt, total		$ 147,309
Non-cash Interest expense on Royalty financing obligation	$ 14,249	1,465
Balance	148,774
Balance	$ 163,023	$ 148,774
Effective interest rate	10.60%	8.50%