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Note 2 - Revenue
12 Months Ended
Dec. 31, 2022
Revenue Recognition [Abstract]  
Revenue Revenue
The Company recorded the following revenues for the years ended December 31 (in thousands):
202220212020
Product sales, net:
ORLADEYO$249,689 $121,865 $133 
RAPIVAB15,156 7,231 483 
Peramivir2,865 7,254 2,685 
Total product sales, net267,710 136,350 3,301 
Royalty revenue2,903 (100)3,381 
Milestone revenue— 15,000 — 
Collaborative and other research and development revenues:  
U.S. Department of Health and Human Services190 5,920 9,231 
Other Collaborations24 — — 
Torii Pharmaceutical Co., Ltd.— — 1,899 
Total collaborative and other research and development revenues214 5,920 11,130 
Total revenues$270,827 $157,170 $17,812 
Royalty revenue from sales of ORLADEYO in Japan by our collaborative partner, Torii, were $1,944 and $690 for the years ended December 31, 2022 and 2021, respectively.