<SEC-DOCUMENT>0001171843-25-003918-index.html : 20250616
<SEC-HEADER>0001171843-25-003918.hdr.sgml : 20250616
<ACCEPTANCE-DATETIME>20250616162222
ACCESSION NUMBER:		0001171843-25-003918
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20250612
FILED AS OF DATE:		20250616
DATE AS OF CHANGE:		20250616

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SANDERS MACHELLE
		CENTRAL INDEX KEY:			0001718020
		ORGANIZATION NAME:           	

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-23186
		FILM NUMBER:		251050401

	MAIL ADDRESS:	
		STREET 1:		C/O NOVAN, INC.
		STREET 2:		4105 HOPSON ROAD
		CITY:			MORRISVILLE
		STATE:			NC
		ZIP:			27560

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BIOCRYST PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0000882796
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				621413174
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		4505 EMPEROR BOULEVARD
		STREET 2:		SUITE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
		BUSINESS PHONE:		919-859-1302

	MAIL ADDRESS:	
		STREET 1:		4505 EMPEROR BOULEVARD
		STREET 2:		SUITE 200
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>ownership.xml
<TEXT>
Document 1 - file: ownership.html

Document 1 - RAW XML: ownership.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>exh_24.htm
<DESCRIPTION>EXHIBIT 24
<TEXT>
Document 2 - file: exh_24.htm

</DOCUMENT>
</SEC-DOCUMENT>