Note 4 - Trade Receivables - Summary of Receivables (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Receivables	$ 1,980	$ 8,243
Billed Revenues [Member]
Receivables	310	2,816
Unbilled Revenues [Member]
Receivables	1,670	5,427
US Department of Health and Human Services [Member]
Receivables	1,675	5,402
US Department of Health and Human Services [Member] \| Billed Revenues [Member]
Receivables	5
US Department of Health and Human Services [Member] \| Unbilled Revenues [Member]
Receivables	1,670	5,402
Royalty Receivables from Partners [Member]
Receivables	305	2,841
Royalty Receivables from Partners [Member] \| Billed Revenues [Member]
Receivables	$ 305	2,816
Royalty Receivables from Partners [Member] \| Unbilled Revenues [Member]
Receivables		$ 25

The total amount due to the entity within one year of the balance sheet date (or one operating cycle, if longer) from outside sources, including trade accounts receivable, notes and loans receivable, as well as any other types of receivables, net of allowances established for the purpose of reducing such receivables to an amount that approximates their net realizable value.

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Name:	us-gaap_ReceivablesNetCurrent
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant