Consolidated Balance Sheets (Current Period Unaudited) - USD ($) $ in Thousands	Mar. 31, 2021	Dec. 31, 2020
Assets
Cash and cash equivalents	$ 226,902	$ 272,127
Restricted cash	4,008	2,221
Investments	13,454	28,239
Trade receivables	18,386	8,646
Inventories	5,113	7,039
Prepaid expenses and other current assets	5,908	5,528
Total current assets	273,771	323,800
Property and equipment, net	7,035	7,113
Other assets	3,625	3,802
Total assets	284,431	334,715
Liabilities and Stockholders’ Equity
Accounts payable	13,529	18,713
Accrued expenses	32,719	33,942
Interest payable	23,547	21,670
Deferred collaboration revenue	405	150
Lease financing obligation	1,001	1,179
Non-recourse notes payable	30,000	30,000
Total current liabilities	101,201	105,654
Lease financing obligation	3,883	3,871
Royalty financing obligation	131,296	124,717
Secured term loan	123,039	119,735
Stockholders’ equity:
Preferred stock, $0.001 par value; shares authorized - 5,000; no shares issued and outstanding	0	0
Common stock, $0.01 par value: shares authorized - 450,000; shares issued and outstanding – 177,670 in 2021 and 176,883 in 2020	1,777	1,769
Additional paid-in capital	1,010,779	1,002,408
Accumulated other comprehensive income	182	3
Accumulated deficit	(1,087,726)	(1,023,442)
Total stockholders’ equity	(74,988)	(19,262)
Total liabilities and stockholders’ equity	$ 284,431	$ 334,715