Note 1 - Significant Accounting Policies- Summary of Receivables (Details) - USD ($) $ in Thousands	Sep. 30, 2018	Dec. 31, 2017
Receivables	$ 3,394	$ 6,117
Billed Revenues [Member]
Receivables	2,078	3,902
Unbilled Revenues [Member]
Receivables	1,316	2,215
US Department of Health and Human Services [Member]
Receivables	1,692	2,062
US Department of Health and Human Services [Member] | Billed Revenues [Member]
Receivables	403	42
US Department of Health and Human Services [Member] | Unbilled Revenues [Member]
Receivables	1,289	2,020
Shionogi and Co. Ltd [Member]
Receivables	35	1,600
Shionogi and Co. Ltd [Member] | Billed Revenues [Member]
Receivables	35	1,600
Shionogi and Co. Ltd [Member] | Unbilled Revenues [Member]
Receivables
Green Cross Corporation [Member]
Receivables	340	1,416
Green Cross Corporation [Member] | Billed Revenues [Member]
Receivables	313	1,388
Green Cross Corporation [Member] | Unbilled Revenues [Member]
Receivables	27	28
Mundipharma International Holdings Limited [Member]
Receivables	75	47
Mundipharma International Holdings Limited [Member] | Billed Revenues [Member]
Receivables	75	47
Mundipharma International Holdings Limited [Member] | Unbilled Revenues [Member]
Receivables
Seqirus UK Limited [Member]
Receivables	1,252	992
Seqirus UK Limited [Member] | Billed Revenues [Member]
Receivables	1,252	825
Seqirus UK Limited [Member] | Unbilled Revenues [Member]
Receivables		$ 167