Note 3 - Collaborative and Other Research and Development Contracts (Details) (USD $)	1 Months Ended	9 Months Ended	1 Months Ended			50 Months Ended	1 Months Ended	9 Months Ended
	May 31, 2010 AECOM and IRL [Member]	Sep. 30, 2014 AECOM and IRL [Member]	Feb. 24, 2011 U.S. Department of Health and Human Services [Member]	Sep. 30, 2009 U.S. Department of Health and Human Services [Member]	Jan. 31, 2007 U.S. Department of Health and Human Services [Member]	Feb. 24, 2011 U.S. Department of Health and Human Services [Member]	Sep. 30, 2013 National Institute of Allergy and Infectious Diseases [Member]	Sep. 30, 2014 National Institute of Allergy and Infectious Diseases [Member]	Sep. 30, 2014 UAB [Member]
Note 3 - Collaborative and Other Research and Development Contracts (Details) [Line Items]
Collaborative Agreement Contract Value					$ 102,661,000
Collaborative Agreement Additional Contract Value			55,000,000	77,191,000
Collaborative Agreement Adjusted Contract Value						234,852,000
Proceeds from Awards for Research and Development Contracts							5,000,000
Expected Receivable from Awards for Research and Development Contracts							28,700,000
Collaborative Agreement Period of Contract							5 years
Collaboration Agreement Additional Payments Received								22,300,000
Milestone Payment Minimum		1,400,000
Milestone Payment Maximum		4,000,000
Annual License Fee Minimum		150,000
Annual License Fee Maximum		500,000
Advance Notice Period for Termination of Agreement		60 days
Stock Issued During Period Value for Modification of License Agreement	5,911,000
Payments for Modification of License Agreement	$ 90,000
Number of Agreements									2
Period of Agreement									25 years
Renewable Period of Agreement									5 years