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Note 1 - Significant Accounting Policies (Details) - Summary of Receivables (USD $)
In Thousands, unless otherwise specified
Sep. 30, 2014
Dec. 31, 2013
Note 1 - Significant Accounting Policies (Details) - Summary of Receivables [Line Items]    
Receivables $ 3,238 $ 2,115
U.S. Department of Health and Human Services [Member] | Billed Revenues [Member]
    
Note 1 - Significant Accounting Policies (Details) - Summary of Receivables [Line Items]    
Receivables 474 90
U.S. Department of Health and Human Services [Member] | Unbilled Revenues [Member]
    
Note 1 - Significant Accounting Policies (Details) - Summary of Receivables [Line Items]    
Receivables 2,764 1,573
U.S. Department of Health and Human Services [Member]
    
Note 1 - Significant Accounting Policies (Details) - Summary of Receivables [Line Items]    
Receivables 3,238 1,663
Shionogi & Co. Ltd. [Member] | Billed Revenues [Member]
    
Note 1 - Significant Accounting Policies (Details) - Summary of Receivables [Line Items]    
Receivables   452
Shionogi & Co. Ltd. [Member]
    
Note 1 - Significant Accounting Policies (Details) - Summary of Receivables [Line Items]    
Receivables   452
Billed Revenues [Member]
    
Note 1 - Significant Accounting Policies (Details) - Summary of Receivables [Line Items]    
Receivables 474 542
Unbilled Revenues [Member]
    
Note 1 - Significant Accounting Policies (Details) - Summary of Receivables [Line Items]    
Receivables $ 2,764 $ 1,573